Low-Dose Naltrexone (LDN) – Immune Modulator

Low-Dose Naltrexone (LDN) refers to using naltrexone at much lower doses (approximately 0.5 mg – 4.5 mg) than the typical 50 mg dose used for addiction treatment. At these low doses, naltrexone has a paradoxical effect on the body’s opioid receptors and immune system. LDN causes a temporary blockade of opioid receptors, which leads to a rebound increase in endorphin production once the blockade wears off. This endorphin surge is believed to help regulate immunity, reduce inflammation, and promote healing.

Frequently Asked Questions

Chronic inflammation can interfere with weight loss. Obese individuals often have elevated internal inflammation. By adding LDN, which decreases inflammation, patients may experience more successful weight loss as their bodies respond better to diet and exercise. In essence, LDN can help “cool off” inflammation that might be hampering metabolism.